the review of literature shows that a strong relationship exists between the symptoms of otolaryngologic diseases and gastroesophageal reflux disease (gerd). it is commonly observed that an extended physical examination is needed to determine the occurrence of gerd. this non-randomized,prospective quasi-experimental study was performed to clinically verify the relationship between otolaryngolog...

a case of a 40-year-old female, in whom a 6-meter long worm (taenia saginata) was found in stomach, is reported here. in this patient, t. saginata upward migration of the worm to the stomach, its rare phenomenon, worm mostly seen in the small intestine. this is mainly because of the high gastric acidity. in this patient, we believe proton pump inhibitor (ppi) use caused hypochlorhydria and coex...

AIMS To systematically review the efficacy on ulcer healing of 1-week combination of a proton pump inhibitor plus two antibiotics and to perform a meta-analysis of randomized clinical trials to evaluate whether 7 days of proton pump inhibitor-based triple therapy is sufficient to heal peptic ulcer. METHODS Studies where 1-week proton pump inhibitor-based triple therapy was administered to hea...

BACKGROUND Studies on the use of low-dose proton pump inhibitor for the maintenance therapy of gastro-oesophageal reflux disease have shown that it might be comparable with standard-dose proton pump inhibitor treatment and superior to standard-dose histamine-2 receptor antagonist therapy. AIM To compare the impact of standard-dose histamine-2 receptor antagonist, low-dose proton pump inhibito...

OBJECTIVE To compare the efficacy of proton pump inhibitor vs. ranitidine bismuth citrate (RBC) with two antibiotics for 1 week in Helicobacter pylori eradication. METHODS Randomized trials comparing 1-week regimens with (i) proton pump inhibitor plus two antibiotics [clarithromycin (C) and amoxycillin (A) or a nitroimidazole (N)]; or (ii) RBC plus the same antibiotics. Eradication was confir...

background : the purpose of this study was to evaluate the effect of apple cider vinegar plus ppi-based triple therapy on eradication of helicobacter pylori (h.pylori) infection. materials and methods : 116 patients with h. pylori infection were included in this randomized clinical trial. patients in control group (n=59) received amoxicillin, clarithromycin, and pantaprazole twice daily. patien...

OBJECTIVE To study the effects of proton pump inhibitors in reducing vomiting, gastrointestinal bleeding, and chest infections in institutionalised neurologically impaired children with gastroesophageal reflux. DESIGN Prospective study. SETTING A regional hospital, Hong Kong. PATIENTS Neurologically impaired children with refractory gastroesophageal reflux. MAIN OUTCOME MEASURES Episode...

H. pylori gastritis and gastric acid closely interact. In H. pylori-positive patients, profound acid suppressive therapy induces a corpus-predominant pangastritis, which is associated with accelerated corpus gland loss and development of atrophic gastritis. Both corpus-predominant and atrophic gastritis have been associated with an increased risk of development of gastric cancer. H. pylori erad...

We investigated the effects of rikkunshito, in combination with a proton pump inhibitor, on symptoms and quality of life in patients with proton pump inhibitor-refractory gastroesophageal reflux disease. The subjects were 47 patients with gastroesophageal reflux disease with residual symptoms such as heartburn following 8 weeks of proton pump inhibitor therapy. We administered these subjects ri...

OBJECTIVE To measure the association between use of proton pump inhibitors and a range of harmful outcomes in patients using clopidogrel and aspirin. DESIGN Observational cohort study and self controlled case series. SETTING United Kingdom General Practice Research Database with linked data from the Myocardial Ischaemia National Audit Project (MINAP) and the Office for National Statistics (...